Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 16, 2025AnemiaOpen Access

Clinical and Laboratory Parameters in Iraqi Alpha‐Thalassemia Pediatric Patients With Different Genetic Profiles, Basrah, Iraq: A Single‐Center Study

View Full Paper
Ask AI
Bookmark
Share

Authors

RJRawshan Zuhair JaberUniversity of BasrahMHMeàad Kadhum HassanUniversity of BasrahSASadeq Khalaf Al-SalaitUniversity of Basrah

Discussion

Loading...

Member takes

Implication

Analytical cross-sectional study identifies mutation types and clinical phenotypes in pediatric alpha-thalassemia patients, indicating significant transfusion needs.

Key Points

  • Most frequent mutation was alpha2 poly A-1, affecting 35 patients, indicating commonality in alpha-thalassemia.
  • Blood transfusions were required for 80% of patients with nondeletional HbH, highlighting clinical implications.
  • Deletional mutations were observed in 45.24% of patients, emphasizing the diversity in genetic mutations of alpha-thalassemia.
  • Iron overload occurred in 11.43% of patients with nondeletional HbH, showing important aspects of treatment management.

Cite This Study

Jaber et al. (2025) studied this question.

synapsesocial.com/papers/68d4565b31b076d99fa5b386https://doi.org/10.1155/anem/5516589
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence, Incidence, Trend, and Complications of Thalassemia in Iraq2017 · 79 citations
  2. 2Revisiting and updating molecular epidemiology of α-thalassemia mutations in Thailand using MLPA and new multiplex gap-PCR for nine α-thalassemia deletion2023 · 20 citations
  3. 3Clinical Manifestations of  -Thalassemia2013 · 124 citations
  4. 4Hematological Analysis in Thai Samples With Deletional and Nondeletional HbH Diseases2017 · 19 citations
  5. 5Alpha thalassemia genotypes in Kuwait2020 · 9 citations