Answers are grounded in this paper and cite their sources.
Case-control study finds elevated uric acid and lipid profile associated with CAD in young adults, suggesting potential early markers.
Background: Coronary artery disease (CAD) is increasingly affecting young adults, particularly in South Asia, where genetic predisposition and lifestyle factors contribute significantly. The role of serum uric acid and lipid profile alterations in early-onset CAD requires further evaluation. Objectives: To assess the association of serum uric acid and lipid profile parameters with CAD in young adults and explore their potential as early, cost-effective biochemical markers for risk assessment. Methods: A hospital-based case-control study was conducted on 50 newly diagnosed young CAD patients and 50 age- and sex-matched healthy controls. Serum uric acid, lipid profile, and other clinical parameters were analyzed and compared between groups. Results: Serum uric acid and lipid profile parameters, including total cholesterol, HDL, and VLDL, were significantly higher in CAD cases. Logistic regression identified total cholesterol and uric acid as independent predictors. Conclusion: Elevated serum uric acid and lipid abnormalities are significantly associated with young-onset CAD.
No takes yet. Share an insight, caveat, or question.
Sarkar et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: