Case series highlights metabolic alkalosis effect during NIV in hospitalized COPD patients, suggesting complications in treatment.
Chronic Obstructive Pulmonary Disease (COPD) is frequently complicated by acute respiratory acidosis during exacerbations requiring hospitalization. Non-invasive ventilation (NIV), particularly BiPAP, is a cornerstone of management. However, during hospitalization, some patients develop metabolic alkalosis, which can impair respiratory compensation and reduce the efficacy of ventilatory support.
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Dhankad et al. (2025) studied this question.
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