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Dynamic EPI measures renal oxygenation in rats during hypoxia and hyperoxia, suggesting potential for renal injury detection.
Motivation: Rapid and dynamic MRI is essential to capture changes in the renal blood oxygen system during stepwise oxygen stimulation. Goal(s): In order to monitor the renal oxygenation various with high-temporal-resolution dynamic imaging by echo planar imaging (EPI) readout. Approach: The dynamic EPI with a 1-second temporal resolution was used to monitor the T2*-weighted signal of the rat kidney under hypoxic and hyperoxic stimulation, applying a second-order system step response model to fit the T2*-weighted signal intensity-time curves. Results: Dynamic EPI has higher temporal resolution and higher model parameter maps quality at the same image resolution. Impact: Dynamic EPI can effectively monitor the changes of renal oxygenation and may be beneficial for renal injury detection.
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Sun et al. (2025) studied this question.
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