This technique improves diastolic dysfunction evaluation by providing enhanced mitral flow measurements, suggesting better accuracy.
Motivation: Conventional 4D flow may find application in diastolic dysfunction evaluations, but is limited by low contrast. Goal(s): Our goal was to extend our previously established 2D PC-SSFP to 4D flow for more robust mitral flow measurements, simultaneously providing E, A, e' and possibly tricuspid regurgitation in a single scan. Approach: We investigated our method in both flow phantoms and healthy volunteers, and compared with 2D CMR and spoiled GRE based 4D flow. Results: Our proposed 4D flow PC-SSFP measured similar flow and maximum velocities, while achieving improved myocardium-blood contrast and higher SNR. Impact: A 4D flow PC-SSFP was developed for more robust diastolic dysfunction evaluations, which estimated mitral inflow and valve velocity in a single scan, and demonstrated agreement with 2D measurements and spoiled GRE based 4D flow, yet improved image quality.
No takes yet. Share an insight, caveat, or question.
Xiang et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: