This editorial emphasizes the role of single-cell multi-omics in uncovering the non-coding transcriptome, suggesting future research directions.
This Editorial introduces my research background as the new Non-coding RNA Section Editor at Hereditas and serves as a call for submissions for the special collection, "Single-Cell Multi-Omic Analysis of Cancer Interactome". Single-cell multi-omic approaches are opening new windows into the non-coding transcriptome, revealing how these molecules shape cellular identity in ways bulk analyses often miss. In this article, I focus on non-coding RNAs and emphasize the importance of integrative systems biology and multi-omics in this field, while also highlighting how these perspectives can guide future discoveries. I cordially invite you to contribute your work by submitting manuscripts to this collection.
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Hua-Sheng Chiu (2025) studied this question.
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