The multivalent passive immune-protective vaccines of egg yolk immunoglobulin Y derived from live or inactivated Pseudomonas anguilliseptica against aquaculture pathogens (P. anguilliseptica and Aeromonas veronii) in goldfish (Carassius auratus)
This study demonstrates effective immune protection against Pseudomonas anguilliseptica and Aeromonas veronii in goldfish, highlighting the role of egg yolk immunoglobulin Y as a vaccine.
Key Points
The IgY antibodies effectively provided passive immunity against P. anguilliseptica and A. veronii in goldfish.
Phagocytic activity of leukocytes was significantly enhanced in goldfish receiving the IgY antibodies.
Histopathological analyses showed no significant tissue damage in the kidneys and spleens of immunized goldfish.
Immunization with egg yolk IgY resulted in reduced inflammatory responses and antioxidant factor expression.