Case report highlights unique occurrence of lip and vulval manifestations in Crohn's disease, suggesting further exploration.
Crohn's disease is a chronic granulomatous inflammatory condition affecting any part of the gastrointestinal tract. Extra-intestinal manifestations affecting the mouth may also occur, with a prevalence varying between 0.5% and 37%. However, vulval involvement is rare with approximately130 reported cases in the literature so far. An extensive literature search has shown isolated lip and vulval involvement as extra-intestinal manifestations of Crohn's disease, with only one reported case of combined vulval and lip involvement.
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Hasan et al. (2025) studied this question.
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