Analysis demonstrates varying drug release kinetics in nanoporous anodic alumina, indicating potential for biosensing applications.
In recent years, nanoporous materials have gained significant attention in research due to their versatile applications in chemical and biological sensing, cell adhesion and culture, template synthesis, and drug delivery. Due to its exceptionally high surface area, nanoporous anodic alumina (NAA) is an ideal material for drug delivery, providing precisely structured nanopores that act as reservoirs for active agents such as drugs or biomolecules. In this work, we investigate the drug release kinetics of NAA with both simple and complex pore structures. The obtained results reveal the influence of pore geometries on drug release rates. Additionally, we study the potential of NAA as an optical biosensing platform for biomolecule detection. This study investigates the real-time biosensing of Human growth hormone (hGH) using a microfluidic optical biosensor based on reflectometric interferometry Fourier spectroscopy (RIFTS). This biosensing platform demonstrates the capability to detect high concentrations of hGH using a cost-effective and fast biosensing system.
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Vallés et al. (2025) studied this question.
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