This review highlights changes in tear composition related to diabetic retinopathy and macular degeneration, indicating potential for early diagnostics.
Key Points
Tear metabolism reflects local eye physiological changes, with relevant metabolites linked to retinal disease progression.
A correlation was found between specific tear metabolites and the stage of retinal pathology, unlike blood concentrations.
The analysis of tear fluid can serve as a non-invasive method for investigating retinal conditions and monitoring disease.
The emerging technologies in tear fluid analysis may facilitate its integration as a liquid biopsy in clinical settings.