Label-free imaging shows distinct alpha-helical and beta-sheet structures in astrocytes, implying structural differences.
With label-free mid-infrared photothermal imaging, alpha-helical accumulations within the fibril extensions of differentiated astrocytes are identified, whereas the cell cytoplasm features a more equal expression of alpha-helical and beta-sheet structures.
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Samolis et al. (2025) studied this question.
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