This review finds that effects of ionizing radiation on innate immunity contribute to tumor microenvironment, suggesting implications for treatment.
CONTENTS Background 1. Cooperation of innate and adaptive immunity cells in pathogenesis in carcinogenesis 2. Neutrophilic granulocytes and cytotoxic T-lymphocytes 3. Neutrophils and antigen-presenting cells 4. Associations of immunocompetent cells with circulating tumor cells 5. Neutrophils and natural killers 6. Tumor microenvironment and angiogenesis 7. Effect of ionizing radiation on innate immunity cells in the tumor microenvironment 8. Ionizing radiation effects modulating the tumor microenvironment 9. The effect of radiation treatment on macrophages and myeloid-derived suppressor cells of the tumor microenvironment Conclusion
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Kodintseva et al. (2025) studied this question.
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