Antibiotics Susceptibility Patterns of Gram-negative Bacteria Isolated From Urine of University of Abuja Female Students

Abstract Urinary tract infections (UTIs) are among the most common bacterial infections, often caused by various pathogenic microorganisms. This study investigated the prevalence and distribution of bacterial isolates in urine samples, focusing on their identification and potential clinical significance. A total of 30 urine samples were analyzed, revealing that Escherichia coli was the most predominant isolate (26.6%), followed by Pseudomonas aeruginosa (20%), Klebsiella pneumoniae (23.3%), Proteus mirabilis (16.6%) and Staphylococcus saprophyticus (13.3%). The total bacteria loads ranged from 2.9×10⁴ to 6.3×10⁵ Cfu/mL and the coliform counts observed ranged from 2.1×10³ to 3.9×10³. The predominance of Gram-negative bacteria, particularly E. coli, highlights its role as a primary etiological agent in UTIs. Staphylococcus saprophyticus, although less frequent, confirms its significance in urinary infections, especially among young females. These findings emphasizes the importance of regular microbiological surveillance, proper hygiene practices, and effective infection control measures.