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CompareM2 simplifies microbial genome analysis through a single-step pipeline, indicating ease of use.
Summary Here, we present CompareM2, a genomes-to-report pipeline for comparative analysis of bacterial and archaeal genomes derived from isolates and metagenomic assemblies. CompareM2 is easy to install and operate, designed in such a way that the user can install the complete software in one step and launch all analyses on a set of microbial genomes (bacterial and archaeal) in a single action. The central results generated via the CompareM2 workflow are emphasized in a portable dynamic report document. Availability and Implementation CompareM2 is a free software that is scalable to a range of project sizes, and welcomes modifications and pull requests from the community on its Git repository at https://github.com/cmkobel/comparem2. Supplementary information Supplementary data are available at Bioinformatics online.
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Kobel et al. (2025) studied this question.
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