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September 20, 2025Open Access

Copper is an intestinal habitat filter affecting the gut microbiota interactions with Salmonella Typhimurium

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Authors

RKRafał KolendaMHMarwa M. HassanAAAinhoa Arrieta-Gisasola

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Overview

On-farm study shows high dietary copper reduces beneficial microbiota and favors salmonella, indicating potential health risks.

Key Points

  • Copper supplementation alters gut microbiota dynamics, reducing beneficial bacteria and enabling salmonella dominance.
  • High-copper diets led to decreased abundance of bifidobacterium and lactobacillus in piglets, increasing pathogen competition.
  • Whole-genome sequencing of 131 species highlighted copper resistance gene acquisition primarily in escherichia.
  • These findings suggest a critical role of copper in altering gut environments, potentially increasing zoonotic pathogen transmission.

Cite This Study

Kolenda et al. (2025) studied this question.

synapsesocial.com/papers/68d469c131b076d99fa664bdhttps://doi.org/10.21203/rs.3.rs-7197766/v1
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