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September 19, 2025VaccinesOpen Access

Correction: Hussain et al. Mind the Age Gap: Expanding the Age Window for mRNA Vaccine Testing in Mice. Vaccines 2025, 13, 370

Muattaz Hussain Agata Ferguson-Ugorenko Robert Macfarlane Nadav Orr Samuel Clarke Michael Wilkinson Linda Horan Yvonne Perrie

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Key Points

Correction highlights the need for broader age criteria in mRNA vaccine testing in mice, aimed at improving results.
Previous studies primarily focused on younger mice, which may not represent older populations effectively.
Methodological adjustments based on age demographics can yield better insights into vaccine efficacy and safety.
This refinement could enhance the translational potential of mRNA vaccines to older human populations.

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Implication

Correction addresses age gap in mRNA vaccine testing, suggesting broader age criteria in mice models.

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Cite This Study

Hussain et al. (2025) studied this question.

synapsesocial.com/papers/68d469ce31b076d99fa66a47 https://doi.org/10.3390/vaccines13090982

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Correction: Omole et al. Safety, Tolerability, and Immunogenicity of the Pneumococcal Vaccines PPSV23 or PCV15 Co-Administered with a Booster Dose of mRNA-1273 SARS-CoV-2 Vaccine in Healthy Adults ≥50 Years of Age. Vaccines 2025, 13, 1922025
2Correction: Dawson et al. A Multi-Country Comparison of Number Needed to Vaccinate for PCV20 and PCV15 in Infants. Vaccines 2026, 14, 188Original Research · 2026
3Mind the Age Gap: Expanding the Age Window for mRNA Vaccine Testing in MiceOriginal Research · 2025 · 6 citations
4Correction: Salloum-Asfar et al. MicroRNA Profiling Identifies Age-Associated MicroRNAs and Potential Biomarkers for Early Diagnosis of Autism. Int. J. Mol. Sci. 2025, 26, 20442025
5Correction: Mawson, A.R.; Croft, A.M. Multiple Vaccinations and the Enigma of Vaccine Injury. Vaccines 2020, 8, 676Original Research · 2026

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Correction: Fukushima et al. Long-Term Immunogenicity of Rabies Pre-Exposure Prophylaxis in Japanese Adult Travelers: Comparison of Dosing Regimens. Vaccines 2025, 13, 11692026
Correction: Trotta et al. Sex and Age-Related Differences in Neuroinflammation and Apoptosis in Balb/c Mice Retina Involve Resolvin D1. Int. J. Mol. Sci. 2021, 22, 62802026
Correction: Wassilak et al. Impediments to Progress Toward Polio Eradication During 2014–2024: Effectively Addressing the Current Challenges. Vaccines 2025, 13, 10602025

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