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September 20, 2025Nephrology Dialysis TransplantationOpen Access

Anti-glomerular basement membrane disease - treatment standard

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Authors

SMStephen P. McAdooCPCharles D. Pusey

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Overview

Review discusses treatment strategies and outcomes in anti-GBM disease, highlighting novel approaches and risks.

Key Points

  • Treatment strategies have improved outcomes in anti-GBM disease, particularly in non-dialysis patients.
  • Autoantibodies against type IV collagen lead to severe complications in half of affected individuals.
  • Diagnosis incorporates clinical features, biopsy findings, and antibody detection to confirm anti-GBM disease.
  • Research is ongoing to explore new therapies and refine treatment for atypical presentations of anti-GBM disease.

Cite This Study

McAdoo et al. (2025) studied this question.

synapsesocial.com/papers/68d46aae31b076d99fa6790ehttps://doi.org/10.1093/ndt/gfaf190
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