Case report describes ocular immune-mediated reactions, including neuroretinitis and neurosensory detachment, following typhoid fever.
Post-fever immune-mediated reactions following typhoid infection are relatively rare. These reactions can manifest variably in the ocular region; however, neuroretinitis, sub-foveal neurosensory detachment, and retinitis are not commonly associated with typhoid fever. We present a case involving a 40-year-old male who reported a sudden decrease in vision in the left eye over the past 20 days, after a diagnosis and treatment for typhoid fever four weeks prior. Fundus examination revealed neuroretinitis with sub-foveal neurosensory detachment in the left eye and retinitis in the right eye. The patient was administered a pulse steroid regimen followed by oral steroids, resulting in visual improvement. Immune-mediated neuroretinitis following typhoid fever appears to respond favourably to steroid treatment, facilitating recovery.
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Gajashree et al. (2025) studied this question.
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