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September 21, 2025Baikal Medical JournalOpen Access

Current and Prospective Approaches to the Treatment of Traumatic Brain Injuries

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Authors

YYYu. A. YurshevTVTkachuk VaMKMaxim Karagyaur

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Overview

Systematic review highlights limited efficacy of existing treatment, suggesting stem cell therapy as a promising approach.

Key Points

  • Treatment of traumatic brain injury faces challenges, with existing methods lacking effectiveness against secondary brain damage.
  • Standard therapy mainly maintains vital functions, but does not address key mechanisms of brain tissue damage after injury.
  • Experimental neuroprotective drugs have shown limited clinical success in improving outcomes for traumatic brain injury patients.
  • Stem cell therapy, particularly utilizing the secretome of mesenchymal stromal cells, represents a promising avenue for future treatment.

Cite This Study

Yurshev et al. (2025) studied this question.

synapsesocial.com/papers/68d46ac231b076d99fa683eahttps://doi.org/10.57256/2949-0715-2025-4-3-63-73
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Modern Approach to the Treatment of Traumatic Brain Injury2024 · 7 citations
  2. 2Stem Cell Therapy for Traumatic Brain Injury: Translational Mechanisms, Biomarkers, and Clinical Trials2026 · 1 citations
  3. 3Key Challenges in Traumatic Brain Injury Treatment: Integrated Mechanisms, Translational Animal Models, and Advanced Drug Delivery Systems2026
  4. 4Neurorestoration After Traumatic Brain Injury: Innovative Therapies for Restoring Function and Quality of Life2025
  5. 5Cell-Based Therapies for the Treatment of Traumatic Brain Injury: Promises and Trajectories2024 · 4 citations