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This is a Quantitative Study study (also classified as: Experimental Study).

September 19, 2025

In silico Digital Twins of Bone Metastasis Enable Investigation of Tumor Progression and Therapy Response.

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The models predict therapeutic outcomes in bone metastasis, enhancing evaluation of treatment strategies.
Simulation of cabozantinib and zoledronic acid shows effective prediction of tumor response in bone metastasis.
Multiscale computational approaches advance understanding of complex interactions in tumor progression.
Agent-based models effectively recapitulate key aspects of bone metastasis, including angiogenesis and resorption.

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In silico models reveal therapy responses in tumor progression, highlighting implications in bone metastasis.

Marsilio et al. (2025) studied this question.

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