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Analysis of a rare type of splenic cyst connected to mesothelial tissue, highlighting its unique pathogenesis.
Introduction: Splenic cysts are rare lesions that are classified as either true (primary) or false (secondary) cysts based on their epithelial lining. The pathogenesis of primary splenic cysts is not well understood, and several hypotheses have been proposed, including the Mesothelial invagination theory, which postulates that during development, the mesothelial lining invades along with the capsule. As the lining has a pluripotent nature, it has the propensity to undergo metaplasia and secretion of fluid, leading to the formation of cysts.
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Alhadeethi et al. (2025) studied this question.
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