Longitudinal Digital Phenotyping of Circadian Rest-Activity Rhythms via Wearables as Biomarkers for Late-Life Function, Cognition, and Neuropsychiatric Health
Longitudinal assessment shows circadian rhythms impact cognitive and neuropsychiatric health in aging populations, indicating potential for intervention.
Key Points
Weaker circadian rhythms are linked to greater disability and cognitive decline in older adults.
Deteriorating rhythm intensity correlates with significant declines in function and cognition, particularly in the elderly.
Digital phenotyping using wearables provides a promising method for early risk detection in aging populations.
Improvement in circadian rhythms indicates stabilization, highlighting their role in neuropsychiatric health.