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September 23, 2025Frontiers in OncologyOpen Access

A gelatin sponge-hemocoagulase sealant for preventing tumor biopsy complications: a dual mechanical and pharmacological barrier

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Authors

XCXiangrui ChenMHMin HuLDLunfei Du

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Overview

This cohort study reduces complications from CT-guided biopsy in patients using gelatin sponge and hemocoagulase, indicating effective intervention.

Key Points

  • The composite technique significantly lowered biopsy complications to 4.6%, compared to a 43% average in existing literature.
  • Among pulmonary biopsies, intervention rates for pneumothorax dropped to 2.38%, vastly improved from 22.1%.
  • D-dimer-stratified dosing considerably reduced hyperfibrinolytic hemorrhage risk by 86.8%, enhancing safety.
  • The method shows promise across various biopsy types, with extrapulmonary procedures reporting zero severe complications.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68d4726431b076d99fa6b8bfhttps://doi.org/10.3389/fonc.2025.1653386
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