Oral gabapentin with and without intravenous dexmedetomidine for postoperative analgesia after modified radical mastectomy: a randomized, controlled, double-blind trial

Key Points

• Duration of postoperative analgesia was significantly longer with dexmedetomidine compared to gabapentin alone, enhancing pain control.
• Total fentanyl consumption was notably lower in the dexmedetomidine group, indicating effective analgesic synergy.
• VAS scores, reflecting pain levels at rest and movement, were significantly lower with dexmedetomidine, highlighting its efficacy in pain relief.
• The study involved 60 patients undergoing modified radical mastectomy under general anesthesia for assessing pain management.