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September 23, 2025Annaly khirurgicheskoy gepatologii = Annals of HPB surgeryOpen Access

Tumor location and histogenesis as risk factors for early complications and mortality following multivisceral surgical procedures with pancreatoduodenectomy

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Authors

VEV. I. EgorovАKА. G. KotelnikovYPYu. I. Patyutko

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Overview

Comparative analysis reveals tumor localization and histogenesis significantly influence postoperative complications, indicating potential for improved patient outcomes.

Key Points

  • Postoperative complications occurred in 65.7% of patients, with pancreatic head cancer showing the most favorable outcomes.
  • Patients with distal common bile duct cancer had a higher risk of pancreatic fistula and wound dehiscence, indicating surgical challenges.
  • Mortality rates were significantly elevated in patients with secondary malignancies of the pancreatic head, suggesting need for careful assessment.
  • This analysis highlights the role of tumor location and type as independent predictors of early postoperative outcomes following complex surgeries.

Cite This Study

Egorov et al. (2025) studied this question.

synapsesocial.com/papers/68d4739d31b076d99fa6bb66https://doi.org/10.16931/1995-5464.2025-3-70-79
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Multivisceral surgeries with pancreatoduodenectomy for gastric cancer: immediate and long-term results2025
  2. 2Prognostic factors for survival after pancreaticoduodenectomy for patients with carcinoma of the pancreatic head region1995 · 1 citations
  3. 3Pancreatic head resection for carcinoma of the ampulla vateri – better long-term prognosis, but more postoperative complications2024 · 2 citations
  4. 4Need for a paradigm shift? Survival post-pancreatoduodenectomy remains poor despite surgical and oncological advances2024
  5. 5The role of tumor location in pancreatic cancer on perioperative outcome and long-term survival2025