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September 23, 2025X-Ray SpectrometryOpen Access

Total X‐Ray Fluorescence Measurement of Spherical Gold Nanoparticle Uptake by PC‐3 Cells: Dual‐Phase Kinetic Uptake and Modelling

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Authors

GTGabriela TraplinRKRaffi KarshafianAPAna Pejović‐Milić

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Overview

Research reveals dual-phase kinetic uptake of gold nanoparticles in PC-3 cells, suggesting improved modeling approaches.

Key Points

  • Uptake of gold nanoparticles increased with higher concentration and smaller size.
  • Kinetic uptake data fit well to a new model with R2 values of 0.8298 to 0.9876.
  • Total reflection x-ray fluorescence enabled precise quantification of nanoparticle interactions.
  • Rate constants of uptake decreased with increased nanoparticle diameter, emphasizing size dependency.

Cite This Study

Traplin et al. (2025) studied this question.

synapsesocial.com/papers/68d4739d31b076d99fa6bbefhttps://doi.org/10.1002/xrs.70041
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