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September 23, 2025BMJ OpenOpen Access

Finding the optimal regimen for Mycobacteroides abscessus treatment (FORMaT) in people with Mycobacteroides abscessus pulmonary disease: a multicentre, randomised, multi-arm, adaptive platform trial

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Authors

TJT de JongTBTimothy BairdHBHelen Louise Barr

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Overview

Randomised multi-arm trial evaluates treatment efficacy and tolerance in Mycobacteroides abscessus infection, indicating a need for better therapy.

Key Points

  • The trial determines effective treatment regimens for mycobacteroides abscessus pulmonary disease.
  • Data collected will help to eliminate ineffective or toxic therapies for this antibiotic-resistant infection.
  • Participants are randomized multiple times to assess the clearance of mycobacteroides abscessus with treatment tolerance.
  • The study aims to identify important biomarkers that inform treatment response and drug pharmacokinetics.

Cite This Study

Jong et al. (2025) studied this question.

synapsesocial.com/papers/68d4739d31b076d99fa6bce0https://doi.org/10.1136/bmjopen-2024-096188
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