Improvement of Maculopathy Associated with Cavitary Optic Disc Anomalies Treated with Topical Anti-glaucoma Medications

Purpose: To report our findings in two cases of maculopathy associated with cavitary optic disc anomalies (CODAs) that were treated successfully with topical anti-glaucoma medications. Methods: Two cases of maculopathy with CODAs were treated with topical anti-glaucoma medications. The ophthalmoscopic and optical coherence tomographic images were recorded before and after beginning the anti-glaucoma medications. Results: Both cases were young women who had a worsening of their visual acuity due to a serous retinal detachment. One woman had an optic disc pit maculopathy, and the other had a large optic disc with an atypical disc coloboma. After treatment with topical anti-glaucoma medications, the subretinal fluid was resolved in both cases and the visual acuity was improved. Conclusion: The improvement of the maculopathy associated with CODAs was observed after the initiation of topical anti-glaucoma eye drops. Although a spontaneous resolution cannot be excluded, these findings suggest that the decrease of intraocular pressure with anti-glaucoma eye drops may be helpful in improving the retinopathy during the follow-up period in selective cases of CODAs.