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September 23, 2025Metabolism and Target Organ DamageOpen Access

Extrahepatic manifestation of metabolic dysfunction-associated steatotic liver disease

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Authors

ASAnil ShenoyAAAijaz AhmedDKDonghee Kim

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Overview

Review highlights systemic effects and shared pathways of metabolic dysfunction-associated steatotic liver disease, indicating the need for comprehensive management strategies.

Key Points

  • Approximately one-third of the global population is affected by metabolic dysfunction-associated steatotic liver disease.
  • Extrahepatic manifestations include cardiovascular disease, type 2 diabetes, and chronic kidney disease.
  • Key mechanisms involve insulin resistance, inflammation, and lipid metabolism dysregulation.
  • Emerging therapeutic strategies for metabolic dysfunction-associated steatotic liver disease are vital for effective management.

Cite This Study

Shenoy et al. (2025) studied this question.

synapsesocial.com/papers/68d4758931b076d99fa6d055https://doi.org/10.20517/mtod.2025.73
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