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September 23, 2025International Journal of Molecular SciencesOpen Access

Special Issue “Gap Junction Channels and Hemichannels in Health and Disease”

Barbara Rijtano Mario Bortolozzi

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Key Points

Connexins are crucial for cell communication and can influence various diseases.
Research on connexins reveals their diverse functions in health and their implications in disease.
Understanding gap junctions and hemichannels can lead to potential therapeutic advancements.
The family of connexins consists of 21 genes in humans, reflecting their complex roles.

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Implication

This special issue highlights the role of connexins in cell communication and disease mechanisms.

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Cite This Study

Rijtano et al. (2025) studied this question.

synapsesocial.com/papers/68d4758931b076d99fa6d201 https://doi.org/10.3390/ijms26199264

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Connexin Gap Junction Channels and Hemichannels: Insights from High-Resolution Structures2024 · 29 citations
2Connexins, cell motility, and the cytoskeletonReview · 2009 · 80 citations
3Regulation of cardiovascular connexins by mechanical forces and junctionsreview · 2013 · 50 citations
4Decoding Connexin Hemichannels: Structure, Function, and Regulatory Mechanisms2025
5Connexin channels and hemichannels are modulated differently by charge reversal at residues forming the intracellular pocket2024 · 2 citations