Observational analysis found lower ovarian reserve in patients with adenomyosis and ovarian endometriosis, suggesting significant reproductive implications.
Abstract This study aims to evaluate the effect of adenomyosis (AM) and ovarian endometriosis (OEM) on ovarian reserve in infertile patients by combining three-dimensional vaginal ultrasound and AMH, FSH and inhibition levels. From March 2023 to May 2025, 69 patients with infertility in our hospital were collected, including 21 patients as the AM group, 18 patients as the OEM group and 30 healthy patients as the healthy group. The AMH, FSH, inhibition and AFC levels were collected for each patient. AMH in the AM group and OEM group was lower than that in the healthy group (P < 0.001). The FSH and inhibin levels in the AM group were lower than those in the healthy group (P < 0.05). AFC in the healthy group was significantly higher than that in the OEM group, and higher in the OEM group than in the AM group (P < 0.05). There is a moderate positive correlation between AMH and AFC (P < 0.05). Both AM and OEM can reduce ovarian reserve. AM can reduce the ovarian reserve indicators AMH, FSH, inhibition and AFC of infertile patients, whereas OEM can reduce AMH and AFC. AFC and AMH are the best indexes to evaluate ovarian reserve.
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Yang et al. (2025) studied this question.
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