Short-course versus long-course antibiotic treatment for ventilator-associated pneumonia: A systematic review and meta-analysis of randomized controlled trials

Q: What type of study is this?

This is a Systematic Review study (also classified as: Meta-Analysis).

Amsalu Fite; Mashood Ahmad Farooqi; Diala Ra’Ed Kamal Kakish; Muhammad Saad Ahmed; Priya Antil; Sai Niharika Tammineedi; NK Gami; Praveen Kumar Komminni; Batoul Ali Taqi; Samreen Rizwan Ahmed Shaikh; Huzaifa Ahmad Cheema; Syeda Sahra; Harpreet Singh; Sharjeel Ahmad; Faran Ahmad; Antoni Torres

doi:10.1080/24745332.2025.2552193

September 25, 2025Canadian Journal of Respiratory Critical Care and Sleep Medicine

Short-course versus long-course antibiotic treatment for ventilator-associated pneumonia: A systematic review and meta-analysis of randomized controlled trials

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Key Points

Short-course antibiotic treatment may increase the risk of pneumonia recurrence in patients, potentially complicating recovery.
Evidence from randomized controlled trials highlights significant outcomes regarding the effectiveness of both treatment durations.
The systematic review and meta-analysis assessed variations in antibiotic durations across different clinical guidelines for VAP.
Understanding the implications of treatment duration is crucial for improving management strategies in VAP patients.

Implication

Systematic review examines short versus long course antibiotic therapy for VAP, indicating potential recurrence issues.

Abstract

RATIONALE Current guidelines recommend a short course of antibiotic therapy for ventilator-associated pneumonia (VAP) caused by nonfermenting gram-negative bacilli (NF-GNB). However, this approach has been associated with an increased risk of pneumonia recurrence.

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Cite This Study

Fite et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3ddeebfec0fc52366d1 https://doi.org/10.1080/24745332.2025.2552193

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Short-course versus long-course antibiotic treatment for ventilator-associated pneumonia: A systematic review and meta-analysis of randomized controlled trials

Key Points

Implication

Abstract

Discussion

Cite This Study

Short-course versus long-course antibiotic treatment for ventilator-associated pneumonia: A systematic review and meta-analysis of randomized controlled trials

Key Points

Implication

Abstract

Discussion

Cite This Study

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