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September 27, 2025Journal of Environmental Exposure AssessmentOpen Access

A health conundrum of bisphenol A and its alternatives: charting a path beyond the structural analogue substitution pitfall

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Authors

YXYang XiangYYYingxin Yu

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Overview

Perspective highlights endocrine disruption issues from BPA alternatives, suggesting safer assessment frameworks.

Key Points

  • Alternatives like bisphenol S and F may pose similar health risks as bisphenol A, including endocrine disruption.
  • Most BPA replacements exhibit harmful properties such as reproductive toxicity and potential neurodevelopmental effects.
  • Regulatory approaches focused on structural analogues may fail to protect public health due to hidden risks.
  • A shift towards a functional safe-by-design strategy is crucial to avoid pitfalls of hazardous substitutions.

Cite This Study

Xiang et al. (2025) studied this question.

synapsesocial.com/papers/68d7be66eebfec0fc5237d04https://doi.org/10.20517/jeea.2025.39
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