Randomized controlled trial shows vitamin D supplementation improves delivery timing in mothers, indicating potential benefits for preterm birth management.
This study investigated the effect of maternal vitamin D intake on delayed delivery time. A randomized, controlled trial was conducted on 175 mothers with preterm labor (intervention group: 89, control group: 86). A dose of 50 000 IU of vitamin D was provided to the intervention group. Neonatal, maternal, and laboratory data were collected. Mothers supplemented with vitamin D gave birth 7.38 ± 7.17 days, while mothers in the control group gave birth 1.09 ± 3.13 days after the onset of birth symptoms (lightening, bloody show, rupture of membranes, nesting, effacement, and dilation). Administering 50 000 IU of vitamin D in pregnant women with premature delivery symptoms was associated with delayed delivery time.
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Zakerihamidi et al. (2025) studied this question.
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