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September 27, 2025International Archives of Allergy and Immunology

Beyond the Rash: How Omalizumab Shapes Mental Health Outcomes in Chronic Spontaneous Urticaria

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Authors

TYTugba Kiratli YolcuVBVolkan BozkurtSDSedat Demirsoy

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Overview

Prospective study shows improvement in anxiety and depression with omalizumab treatment for CSU patients, indicating benefits beyond skin symptoms.

Key Points

  • Omalizumab treatment significantly reduces anxiety and depression scores in chronic spontaneous urticaria patients.
  • 91% of patients showed notable reduction in Urticaria Activity Score, reflecting clinical significance.
  • Assessment included Urticaria Activity Score and Hospital Anxiety and Depression Scale, evaluated at six months.
  • Psychological benefits observed regardless of baseline anxiety and depression levels indicate potential broader treatment implications.

Cite This Study

Yolcu et al. (2025) studied this question.

synapsesocial.com/papers/68d7be70eebfec0fc52386c8https://doi.org/10.1159/000548659
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