Observational analysis identifies somatic variants in familial myeloma genes in patients, suggesting genetic roles in disease.
Background Genetic factors associated with familial multiple myeloma (MM) have been studied, yet the somatic engagement of germline predisposition genes remains underexplored. This study aims to systematically analyze somatic variants in previously reported germline familial myeloma predisposition genes.
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Akkuş et al. (2025) studied this question.
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