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September 24, 2025Plastic & Reconstructive Surgery

Discussion: Cost Effectiveness of Prophylactic Mastectomy and Autologous Flap Reconstruction in BRCA1/2-Positive Patients

Danielle H. Rochlin Evan Matros

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Key Points

The discussion evaluates the cost effectiveness of prophylactic mastectomy in BRCA1/2-positive patients.
Findings highlight autologous flap reconstruction's financial implications, suggesting significant benefits.
The analysis aims to inform decision-making for patients considering preventive surgical options.
Understanding cost effectiveness may guide healthcare policies regarding BRCA-related interventions.

Implication

Discussion assesses cost effectiveness of prophylactic mastectomy and reconstruction in BRCA1/2-positive patients, indicating potential benefits.

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Cite This Study

Rochlin et al. (2025) studied this question.

synapsesocial.com/papers/68d7e84439bbb06045426b4c https://doi.org/10.1097/prs.0000000000012235

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Abstract PO3-08-12: Oncologic Safety and Preventive Impact of Nipple-Sparing Mastectomy in BRCA1/2 Mutation Carriers: A Multicenter Retrospective Study of the Korea Robot-Endoscopy Minimal Access Breast Surgery Study Group (KoREa-BSG)2024
2Abstract PO5-23-06: Predictive Factors for Reconstructive Method and Outcomes in Mutation-Positive Breast Cancer Patients2024
3The comparison of effectivity in breast cancer prevention between skin sparing and subcutaneous mastectomy – 20 years of experience2024 · 2 citations
4Abstract PD12-01: Surgical management of young BRCA1/2 carriers with early onset breast cancerCohort Study · 2026
5Discussion: Robotic Nipple-Sparing Mastectomy and Breast Reconstruction with Profunda Artery Perforator Flaps2025

More related papers

Abstract PS3-01-14: Oncological and Surgical Outcomes of Risk Reducing Nipple Sparing Mastectomy in Germline Pathogenic Variant Carriers2026
From Awareness to Advancement: The Breast Reconstruction Issue2025
Oncological safety and preventive impact of nipple-sparing mastectomy in patients with <i>BRCA1/2</i> mutation: multicentre study of the Korea Robot-endoscopy Minimal Access Breast Surgery Study Group (KoREa-BSG)2025

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