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September 25, 2025Indian Journal of Pharmacy and PharmacologyOpen Access

Acute toxicity, renoprotective evaluation, and histopathological assessment of natural flavonoids against gentamicin-induced nephrotoxicity

Vijaykumar Yelwantge Vivek Chauhan

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Key Points

Flavonoids demonstrated significant renoprotective effects against gentamicin-induced nephrotoxicity.
Histopathological assessment showed reduced kidney damage in treated rats compared to control.
This evaluation involved comparing toxicity levels caused by gentamicin against natural flavonoids.
Flavonoids may serve as a potential therapeutic strategy to alleviate acute kidney injury.

Implication

Research reveals acute toxicity of gentamicin in rats, with flavonoids showing potential renoprotective effects during histopathological evaluation.

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Cite This Study

Yelwantge et al. (2025) studied this question.

synapsesocial.com/papers/68d9052941e1c178a14f56e8 https://doi.org/10.18231/j.ijpp.20030.1758795255

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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4Boosting impacts of <i>Acacia nilotica</i> against hepatic toxicity induced by gentamicin: biochemical, anti-inflammatory and immunohistochemical study2024 · 2 citations
5Histopathological Evidence of Resveratrol-Mediated Renal Protection Against Gentamicin Toxicity in RatsOriginal Research · 2026

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