Editorial highlights emerging evidence on intranasal dexmedetomidine for sedation and reducing emergence agitation in surgery.
AnaesthesiaEarly View Editorial Expanding the role of intranasal dexmedetomidine in peri-operative care This article relates to: Pre-operative dexmedetomidine nasal spray and emergence agitation in adults undergoing ear, nose and throat surgery: a randomised controlled trial Dan Wang, Wei Dou, Jing-hui Hu, Lei Huang, Hong Liu, Fu-hai Ji, Ke Peng, Anaesthesia First Published online: August 8, 2025 Vivian M. Yuen, Vivian M. Yuen orcid.org/0000-0003-1803-0657 Department of Anesthesiology, Hong Kong Children's Hospital, Hong Kong, SAR, ChinaSearch for more papers by this authorMichael G. Irwin, Corresponding Author Michael G. Irwin [email protected] orcid.org/0000-0001-5801-274X @mgirwin Department of Anaesthesiology, University of Hong Kong, Hong Kong, SAR, China Correspondence to: Michael G. Irwin Email: [email protected]Search for more papers by this author Vivian M. Yuen, Vivian M. Yuen orcid.org/0000-0003-1803-0657 Department of Anesthesiology, Hong Kong Children's Hospital, Hong Kong, SAR, ChinaSearch for more papers by this authorMichael G. Irwin, Corresponding Author Michael G. Irwin [email protected] orcid.org/0000-0001-5801-274X @mgirwin Department of Anaesthesiology, University of Hong Kong, Hong Kong, SAR, China Correspondence to: Michael G. Irwin Email: [email protected]Search for more papers by this author First published: 26 September 2025 https://doi.org/10.1111/anae.70011 1 Department of Anesthesiology, Hong Kong Children's Hospital, Hong Kong SAR, China 2 Department of Anaesthesiology, University of Hong Kong, Hong Kong SAR, China The editorial accompanies an article by Wang et al., Anaesthesia 2025; https://doi.org/10.1111/anae.16726. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechatBluesky References 1Lepouse C, Lautner CA, Liu L, Gomis P, Leon A. Emergence delirium in adults in the post-anaesthesia care unit. Br J Anaesth 2006; 96: 747–753. https://doi.org/10.1093/bja/ael094. 10.1093/bja/ael094 CAS PubMed Web of Science® Google Scholar 2Yu D, Chai W, Sun X, Yao L. Emergence agitation in adults: risk factors in 2000 patients. 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