Research shows improved embryo production in vitro using 3D culture models and replicating oviduct conditions, indicating better outcomes for reproductive biotechnology.
Oviduct represents the original place of fertilisation and early embryo development in all the domestic animals. In past time it has been considered a mere channel but new reproductive biotechnology approaches suggested the need of structurally and functionally efficient oviductal environment for in vitro embryo production. Recreating the oviductal microenvironment in IVP systems represents a paradigm shift in reproductive biotechnology. By incorporating reproductive fluids and utilising advanced 3D culture models could be reduced adverse IVP outcomes, and bring assisted reproduction closer to its natural counterpart.
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Palle et al. (2025) studied this question.
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