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September 25, 2025Cancer Biotherapy and Radiopharmaceuticals

CT-Guided Percutaneous Radioactive ¹²⁵I Brachytherapy for Locally Advanced Pancreatic Cancer

Peng Du Liangliang Meng Zenan Chen Xiao Zhang

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Key Points

Brachytherapy may reduce tumor size in patients with locally advanced pancreatic cancer, leading to improved outcomes.
Patients receiving 125I implantation had promising results, with a notable reduction in pain reported.
Assessment through a prospective observational study indicates strong safety and efficacy for this treatment approach.
These findings support further exploration of 125I brachytherapy in clinical settings for pancreatic cancer.

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Implication

Brachytherapy shows efficacy for treating locally advanced pancreatic cancer, suggesting a safe approach with 125I implants.

Abstract

Purpose: To explore the efficacy and safety of 125I source implantation via a coaxial puncture in treating locally advanced pancreatic cancer (LAPC).

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Cite This Study

Du et al. (2025) studied this question.

synapsesocial.com/papers/68d913b24ddcf71ba560c0d5 https://doi.org/10.1177/10849785251380365

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