Laxative‐induced contact burns from accidental ingestion of senna in a 2‐year‐old female

Senna (sennosides) is a natural stimulant laxative containing anthraquinone glycosides, commonly used to treat constipation. We present the case of a healthy 2‐year‐old female (~12.5 kg) who is not yet toilet‐trained and accidentally ingested a single 15 mg chocolate‐flavored sennoside chew (1.2 mg/kg). This led to sharply demarcated erythema, pain, and blisters in her diaper area. In the emergency department, the blisters were treated by unroofing, topical mupirocin application, a petrolatum dressing, and a 5‐day course of oral cephalexin. The burn injury healed without complications at a follow‐up visit. This case highlights the risk of senna‐induced burns in diapered toddlers, as prolonged stool‐skin contact can cause blistering that mimics abusive injury. Inquiries about sennoside use should be made when perineal burns are observed in pre‐continent children to prevent misdiagnosis of child abuse. Preventive measures, including caregiver education, child‐resistant packaging, and safe medication storage, are essential.