What type of study is this?

This is a Quantitative Study study (also classified as: Experimental Study).

Identification Of CDKN2A Somatic Mutations in HCC Patients: Insights from NGS in An Egyptian Cohort

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Analysis reveals CDKN2A mutations in 28.6% of HCC patients using next-generation sequencing, suggesting potential insights into hepatocarcinogenesis.

CDKN2A mutations were detected in 28.6% of patients with hepatocellular carcinoma.
Ten somatic variants were identified across six patients, including single-nucleotide and copy number variants.
Next-generation sequencing was utilized to analyze circulating cell-free DNA in this Egyptian cohort of HCC patients.
These findings may indicate CDKN2A's role in hepatocarcinogenesis but further research is needed to clarify its clinical relevance.

Abdel‐Wahab et al. (2025) studied this question.

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View Full Paper

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Authors

Analysis reveals CDKN2A mutations in 28.6% of HCC patients using next-generation sequencing, suggesting potential insights into hepatocarcinogenesis.

CDKN2A mutations were detected in 28.6% of patients with hepatocellular carcinoma.
Ten somatic variants were identified across six patients, including single-nucleotide and copy number variants.
Next-generation sequencing was utilized to analyze circulating cell-free DNA in this Egyptian cohort of HCC patients.
These findings may indicate CDKN2A's role in hepatocarcinogenesis but further research is needed to clarify its clinical relevance.

Abdel‐Wahab et al. (2025) studied this question.

View Full Paper

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