Retrospective analysis found a 9.4% rise in CRE incidence with each 10°C increase in temperature, suggesting climate's role in antimicrobial resistance.
Carbapenem-resistant Enterobacteriaceae (CRE) infections pose a major public health threat with limited treatment options and high mortality. Using national surveillance data from South Korea (2018–2021), we conducted a time-series analysis to assess associations between monthly CRE incidence, minimum temperature, and meropenem usage. A 10°C rise in minimum temperature was associated with a 9.4% increase in CRE incidence (95% Confidence Interval: 5.0–13.9%). Findings suggest temperature as an environmental driver of antimicrobial resistance, supporting integration of climate data into surveillance.
No takes yet. Share an insight, caveat, or question.
Kim et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: