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October 1, 2025Emerging infectious diseases2 citationsOpen Access

Retrospective Analysis of Historical Listeria monocytogenes Clinical Isolates, New York, USA, 2000–20211

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HSHilal SamutDMDamaris V. Mendez-VallellanesHHH. H. Hoyt

Key Points

  • Clusters of listeria monocytogenes were identified from historical clinical isolates, indicating persistent local outbreaks.
  • Whole-genome sequencing revealed 321 clinical isolates forming 85 clusters, including 14 with outbreak codes.
  • Isolation of food and environmental samples related to clinical cases underscores the complexity of listeriosis transmission.
  • Clusters spanned years and included geographically close isolates, indicating long-term monitoring is crucial.

Abstract

We used whole-genome sequencing data to investigate historical Listeria monocytogenes clinical (n = 1,046) and nonclinical (n = 1,325) isolates from New York, USA. Applying a threshold of 10 years apart; 33 clusters included isolates from the same or contiguous counties. Seventeen clusters included food and environmental isolates highly related to clinical isolates. These findings suggest that some listeriosis clusters can be local and span a long period, demonstrating the importance of investigating small, localized listeriosis cases with closely related isolates, even over long timeframes.

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Cite This Study

Samut et al. (2025) studied this question.

synapsesocial.com/papers/68dd89e6fe798ba2fc497ef0https://doi.org/10.3201/eid3110.241876
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