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October 1, 2025Open Access

Cataract Review of Integrating Pathogenic Mechanisms, Experimental Models, and Therapeutic Development

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Authors

LLLang LangKXKai‐Da XuXZXin-Wen Zhang

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Overview

Review highlights the role of oxidative stress in cataract and suggests pharmacotherapy implications.

Key Points

  • Oxidative stress is identified as the principal pathogenic mechanism of cataract, with multiple contributing factors.
  • The review emphasizes the significance of pharmacotherapy, including antioxidants and aldose reductase inhibitors.
  • This comprehensive approach includes insights from animal models in developing therapeutic strategies.
  • Addressing cataract's burden requires multi-target strategies beyond traditional surgical interventions.

Cite This Study

Lang et al. (2025) studied this question.

synapsesocial.com/papers/68dd91cffe798ba2fc498ca8https://doi.org/10.22541/au.175925536.65883334/v1
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Also Consider

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  1. 1Pathophysiology, Diagnosis and Management of Cataract2024 · 3 citations
  2. 2Comprehensive Modalities for Cataract Management: Preventive, Surgical, and Non-Surgical Approaches Using Conventional and Nanotechnology-Based Therapies2026
  3. 3Perspective of Cataract and Oxidative Stress2024
  4. 4The Link between Caveolae, Metabolic Syndrome, and Cateractogenesis: A Mechanistic Hypothesis2025
  5. 5Reactive oxygen species and oxidative stress in ocular disease: from molecular mechanisms to targeted therapies2025 · 7 citations