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October 1, 2025ToxicsOpen Access

Association of Exposure to Phthalate Metabolites with Antenatal Depression in US Pregnant Women

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Authors

PDPallavi DubeyCTChinthana ThangavelAYAbdelrahman Yousif

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Overview

Cross-sectional study shows association between phthalate metabolites and antenatal depression severity in pregnant women, suggesting potential health impacts.

Key Points

  • Higher exposure to phthalate metabolites is linked with increased depression symptom scores in pregnant women.
  • All examined phthalates, except mono (carboxyoctyl) and mono-isononyl phthalate, were associated with elevated PHQ-9 scores.
  • Data from the National Health and Nutrition Examination Survey was analyzed to determine the relationship between phthalate exposure and depression.
  • Results highlight the concerning potential impact of phthalate metabolites on mental health during pregnancy.

Cite This Study

Dubey et al. (2025) studied this question.

synapsesocial.com/papers/68dd91d5fe798ba2fc498ec9https://doi.org/10.3390/toxics13100838
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