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October 1, 2025Open Access

Combined proteomics and metabolomics analyses revealed molecular signatures associated with proliferative diabetic retinopathy

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Authors

YCYixin CuiLRLingna RaoDLDongli Li

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Overview

Analyses reveal dysregulated proteins and metabolites in proliferative diabetic retinopathy, suggesting novel biomarkers and therapeutic targets.

Key Points

  • Significant dysregulation of proteins and metabolites was observed in patients with proliferative diabetic retinopathy.
  • Seven key proteins and six metabolites were identified, highlighting pathways linked to inflammation and vascular issues.
  • The combination of proteomics and metabolomics allowed for a comprehensive understanding of diabetic retinopathy mechanisms.
  • Identifying biomarkers may lead to new diagnostic tools and treatment strategies for diabetic retinopathy.

Cite This Study

Cui et al. (2025) studied this question.

synapsesocial.com/papers/68dd91d5fe798ba2fc498fe5https://doi.org/10.21203/rs.3.rs-7345162/v1
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