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Analysis reveals three clinical groups for cystic fibrosis patients, indicating a need for personalized rehabilitation programs.
To assess the clinical severity of health state, we included 33 patients with cystic fibrosis (aged 18-37) in our study. All the patients were divided into three groups according to the severity of the clinical presentations of respiratory lesions (latent, moderate and expressed). In order to develop an algorithm of the grouping of the patients with cystic fibrosis, a classification tree was built for the examined patients (training sorting). Using methods of cluster analysis it was proved that cystic fibrosis patients are divided into three clusters depending on the severity of bronchopulmonary lesions. The cluster distribution of the patients corresponded to that in clinical groups selected out in the empirical way. The research results can be used to differentiate the patients in the development of medical rehabilitation programs.
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Natalya Manovitskaya (2014) studied this question.
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