Challenges and Opportunities in Nanotherapeutics Targeted for Central Nervous System Disorders

Joel Yong; Karen Hakobyan; Zaheri Mahmud; Daniel Johnson; Jacob Lee; Ashish D. Diwan; Zi Gu; Gila Moalem‐Taylor; Guangzhao Mao

doi:10.1039/d5nr02463c

January 1, 2025NanoscaleOpen Access

Challenges and Opportunities in Nanotherapeutics Targeted for Central Nervous System Disorders

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Key Points

CNS disorders present complex challenges, with neuroinflammation limiting treatment effectiveness.
Key barriers include the intricate structure of the CNS and a limited understanding of underlying diseases.
Nanotherapeutics may offer innovative solutions to overcome these barriers and improve treatment outcomes.
Future research is crucial to enhance drug delivery strategies to the CNS and mitigate disease challenges.

Implication

This analysis highlights significant issues in nanotherapeutics for CNS disorders, suggesting new treatment pathways.

Abstract

Central nervous system (CNS) disorders represent some of the most challenging problems for modern medicine. The complexity of the CNS structure, incomplete understanding of disease, chronic neuroinflammation, and physiological barriers...

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Cite This Study

Yong et al. (2025) studied this question.

synapsesocial.com/papers/68de5d9383cbc991d0a1fe6c https://doi.org/10.1039/d5nr02463c

View Full Paper

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Challenges and Opportunities in Nanotherapeutics Targeted for Central Nervous System Disorders

Key Points

Implication

Abstract

Discussion

Cite This Study

Challenges and Opportunities in Nanotherapeutics Targeted for Central Nervous System Disorders

Key Points

Implication

Abstract

Discussion

Cite This Study

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